| ROUND | PICK | | | PLAYER | POSITION |
| 1 | 1 |  |  | Evan Longoria | 3B |
| 1 | 2 | |  | David Price | SP |
| 1 | 3 |  |  | Jay Bruce | RF |
| 1 | 4 | |  | Clayton Kershaw | SP |
| 1 | 5 |  |  | Max Scherzer | SP |
| 1 | 6 |  |  | Alexei Ramirez | SS |
| 1 | 7 |  |  | Johnny Cueto | SP |
| 1 | 8 |  |  | Chris Volstad | SP |
| 1 | 9 | |  | Travis Snider | RF |
| 1 | 10 | |  | Chris Davis | 1B |
| 1 | 11 |  |  | Justin Masterson | SP |
| 1 | 12 |  |  | Hiroki Kuroda | SP |
| 1 | 13 |  |  | Jeff Samardzija | RP |
| 1 | 14 |  |  | Pablo Sandoval | 3B |
| 1 | 15 | |  | Dexter Fowler | CF |
| 1 | 16 |  |  | John Baker | C |
| 2 | 1 | |  | Denard Span | RF |
| 2 | 2 | |  | Alicides Escobar | SS |
| 2 | 3 | |  | Jose Arredondo | RP |
| 2 | 4 | |  | Mat Gamel | 3B |
| 2 | 5 | |  | Mike Aviles | SS |
| 2 | 6 | |  | Matt Joyce | LF |
| 2 | 7 | |  | Chris Dickerson | LF |
| 2 | 8 | |  | Daniel Murphy | 1B |
| 2 | 9 | |  | Gio Gonzalez | SP |
| 2 | 10 | |  | Lou Marson | C |
| 2 | 11 | |  | Garrett Mock | RP |
| 2 | 12 | |  | Sergio Romo | RP |
| 2 | 13 | |  | James Mcdonald | RP |
| 2 | 14 | |  | Chris Getz | 2B |
| 2 | 15 | |  | Cory Wade | RP |
| 2 | 16 | |  | Jesse Carlson | RP |
| 3 | 1 | |  | Taylor Teagarden | C |
| 3 | 2 |  |  | Ben Zobrist | 2B |
| 3 | 3 |  |  | Blake DeWitt | 3B |
| 3 | 4 | |  | Brad Ziegler | RP |
| 3 | 5 | |  | Nick Adenhart | SP |
| 3 | 6 | |  | Jed Lowrie | SS |
| 3 | 7 |  |  | Matt Harrison | SP |
| 3 | 8 | |  | Gabe Gross | CF |
| 3 | 9 | |  | Ramon Ramirez | SP |
| 3 | 10 |  |  | Kosuke Fukudome | RF |
| 3 | 11 | |  | Carlos Gonzalez | CF |
| 3 | 12 | |  | Greg Smith | SP |
| 3 | 13 | |  | Michael Bowden | SP |
| 3 | 14 | |  | Scott Elbert | RP |
| 3 | 15 | |  | Jonathan Niese | SP |
| 3 | 16 | |  | Reid Brignac | SS |
| 4 | 1 | |  | Steven Shell | RP |
| 4 | 2 | |  | Ryan Hanigan | C |
| 4 | 3 | |  | Joel Hanrahan | RP |
| 4 | 4 | |  | Scott Lewis | SP |
| 4 | 5 | |  | Brett Gardner | LF |
| 4 | 6 | |  | Frank Francisco | CP |
| 4 | 7 | |  | Aaron Cunningham | RF |
| 4 | 8 | |  | Brian Bruney | RP |
| 4 | 9 | |  | Darren Oliver | RP |
| 4 | 10 | |  | Brandon League | RP |
| 4 | 11 | |  | Chris Perez | RP |
| 4 | 12 | |  | Ryan Shealy | 1B |
| 4 | 13 | |  | Max Ramirez | C |
| 4 | 14 | |  | Chad Bradford | RP |
| 4 | 15 | |  | Matt Antonelli | 2B |
| 4 | 16 | |  | John Grabow | RP |
| 5 | 1 | |  | Alfredo Aceves | RP |
| 5 | 2 | |  | Jose Bautista | 3B |
| 5 | 3 | |  | Gaby Sanchez | 1B |
| 5 | 4 | |  | Travis Ishikawa | 1B |
| 5 | 5 | |  | Josh Geer | SP |
| 5 | 6 | |  | Dennys Reyes | RP |
| 5 | 7 | |  | Kila Ka'aihue | 1B |
| 5 | 8 | |  | Robinson Tejeda | RP |
| 5 | 9 | |  | Matt Albers | SP |
| 5 | 10 | |  | Rocco Baldelli | CF |
| 5 | 11 | |  | Jesse Crain | RP |
| 5 | 12 | |  | Collin Balester | SP |
| 5 | 13 | |  | Jason Motte | RP |
| 5 | 14 | |  | Jody Gerut | LF |
| 5 | 15 | |  | Nick Masset | RP |
| 5 | 16 | |  | Mike Lincoln | RP |
| 6 | 1 | |  | Micah Hoffpauir | 1B |
| 6 | 2 | |  | Norris Hopper | CF |
| 6 | 3 | |  | Daryl Thompson | SP |
| 6 | 4 | |  | Phil Coke | RP |
| 6 | 5 | |  | Carlos Rosa | SP |
| 6 | 6 | |  | Chris Carter | LF |
| 6 | 7 | |  | Scott Hairston | LF |
| 6 | 8 | | | | |
| 6 | 9 | | | | |
| 6 | 10 | |  | Jeff Larish | 1B |
| 6 | 11 | |  | Jeff Bailey | 1B |
| 6 | 12 | |  | Brandon Boggs | LF |
| 6 | 13 | |  | David Purcey | SP |
| 6 | 14 | |  | Eric Hurley | IR |
| 6 | 15 | |  | Will Venable | RF |
| 6 | 16 | |  | Alex Hinshaw | RP |
| 7 | 1 | |  | Dusty Ryan | C |
| 7 | 2 | |  | Scott Feldman | SP |
| 7 | 3 | |  | Edgar Gonzalez | 2B |
| 7 | 4 | |  | Brian Barton | LF |
| 7 | 5 | |  | Clete Thomas | RF |
| 7 | 6 | |  | Craig Hansen | RP |
| 7 | 7 | | | | |
| 7 | 8 | | | | |
| 7 | 9 | |  | Anderson Hernandez | 2B |
| 7 | 10 | |  | Nyjer Morgan | CF |
| 7 | 11 | | | | |
| 7 | 12 |  |  | Gregor Blanco | CF |
| 7 | 13 | |  | Seth Smith | RF |
| 7 | 14 | |  | Jaime Garcia | RP |
| 7 | 15 | |  | Fernando Perez | RF |
| 7 | 16 | |  | Chris Ray | RP |
| 8 | 1 | |  | Joaquin Arias | SS |
| 8 | 2 | | | | |
| 8 | 3 | | | | |
| 8 | 4 | | | | |
| 8 | 5 | |  | Angel Pagan | CF |
| 8 | 6 | |  | Ryan Tucker | SP |
| 8 | 7 | | | | |
| 8 | 8 | | | | |
| 8 | 9 | | | | |
| 8 | 10 | |  | Emmanuel Burriss | SS |
| 8 | 11 | | | | |
| 8 | 12 | |  | David Robertson | RP |
| 8 | 13 | |  | Michael Aubrey | 1B |
| 8 | 14 | |  | Jon Meloan | RP |
| 8 | 15 | |  | Billy Sadler | RP |
| 8 | 16 | |  | Henry Blanco | C |
| 9 | 1 | |  | Jeff Bennett | RP |
| 9 | 5 | |  | Mitch Maier | RF |
| 9 | 10 | |  | Jamey Carroll | 2B |
| 9 | 12 | |  | Jose Mijares | RP |
| 9 | 13 | |  | Jonny Gomes | LF |
| 9 | 14 | |  | Jason Windsor | SP |
| 9 | 15 | |  | Alberto Callaspo | 2B |
| 10 | 1 | |  | Joe Inglett | 2B |
| 10 | 5 | |  | Nick Evans | LF |
| 10 | 10 | |  | Troy Patten | SP |
| 10 | 12 | |  | Willy Aybar | 3B |
| 10 | 13 | |  | Ramon Troncoso | RP |
| 10 | 15 | |  | Cesar Izturis | SS |
| 11 | 1 | |  | Cody Ransom | SS |
| 11 | 5 | |  | Luis Montanez | RF |
| 11 | 12 | |  | Yoslan Herrera | SP |
| 12 | 1 | |  | Matt Tuiasosopo | SS |
| 12 | 12 | |  | Wilson Betemit | 3B |
| 13 | 1 | |  | Joe Mather | LF |
| 13 | 12 | |  | Carl Pavano | SP |
| 14 | 1 | |  | Roy Corcoran | RP |
| 14 | 12 | |  | Luis Valbuena | 2B |
| 15 | 1 | |  | Kyle McClellan | RP |
| 15 | 12 | |  | Bryan LaHair | 1B |
| 16 | 1 | |  | Nick Hundley | C |
| 16 | 12 | |  | John Bowker | 1B |
|